I've been experimenting with PlayOnLinux (v4.2.10-2 on Ubuntu 16.04) under a VMWare Fusion instance (since I'm having problems with Wine and DRI/OpenGL on my workstation, explained here: https://www.playonlinux.com/en/topic-14897-Crash_with_qlibGL_errorq_despite_necessary_files_being_present.html). When I launch a 'bare' X desktop it starts at 800x600. So I adjust the size using 'xrandr --size 1280x1024'. However, if I launch PlayOnLinux after doing the resize, the fonts POL uses are all excessively large, as shown in this screenshot (Firefox in background provides a scale comparison for 'normal' fonts). If I start POL before resizing the desktop, the fonts look normal and stay that way.