Bonjour,
Merci Petch pour les informations et l'aide.
Voici donc ma première version du script, je l'ai testée sous Debian 7.2 AMD 64, avec la version Wine 1.6.2 64, ça passe 
J'ai une question, quelle est la commande qui permet de tester une précédente installation (un test sur le $Prefix) ?
A suivre,
#!/bin/bash
#
# Date : 2016-02-08
# Last revision : 2016-02-
# Author : Jacques-Olivier jacques-olivier AT ouvaton.org
# Tested on : Debian 7 64
# Wine version used to test : 1.6.2 AMD 64
#
# Pre-requisties :
# Distribution tested : Debian 7 and 8.2 AMD 64 / Xubuntu 15.10 AMD 64
#
# TODO
#
# Make tests under Debian 8.2 / Xubuntu 15.10
# Make a test for a previously installation, and ask to erase the Prefix before installation
#
[ "$PLAYONLINUX" = "" ] && exit 0
source "$PLAYONLINUX/lib/sources"
# Variables definitions
TITLE="Ninelives"
PREFIX="smokymonkeys"
EDITOR="SmokyMonkeys"
AUTHOR="Jacques-Olivier"
GAME_URL="http://ninelives.smokymonkeys.com"
PICTURES_URL="http://ninelives.ouvaton.org/img/playonlinux"
WORKING_WINE_VERSION="1.6.2"
# Downloading pictures of the game
# The left.jpg picture must be about 150x356px and the top.jpg picture must be about 60x60px
POL_GetSetupImages "$PICTURES_URL/top.png" "$PICTURES_URL/left.png" "$PICTURES_URL/logo-48x48.png" "$PICTURES_URL/logo-22x22.png" "$TITLE"
# Starting the script
POL_SetupWindow_Init
POL_Debug_Init
POL_SetupWindow_presentation "$TITLE" "$EDITOR" "$GAME_URL" "$AUTHOR" "$PREFIX"
# Setting prefix path
POL_Wine_SelectPrefix "$PREFIX"
# Downloading wine if necessary and creating 64-bit prefix
POL_System_SetArch "AMD64"
POL_Wine_PrefixCreate "$WORKING_WINE_VERSION"
# Asking for the last setup installation file
POL_SetupWindow_question "Did you download the latest version of $TITLE from $GAME_URL ?" "Before installing ..."
POL_SetupWindow_InstallMethod "LOCAL"
# Begin game installation
cd "$HOME"
POL_SetupWindow_browse "$(eval_gettext 'Please select the setup file to run')" "$TITLE"
SETUP_EXE="$APP_ANSWER"
POL_Wine start /unix "$SETUP_EXE"
POL_Wine_WaitExit "$TITLE"
#Create shortcuts
POL_Shortcut "Ninelives.exe" "$TITLE" "" "Game;RPGGame;"
POL_SetupWindow_Close
exit
Editado por: JacquesOlivier