I tried installing PlayOnMac on a MacBook Pro, which does not has Bitdefender installed.
The installation of POM 4.4 works fine!
Unfortunately, the installation of exe-files always stuck in two processes:wine32on64-preloader "control" and "wineboot" (the "wheel" keeps on turning during the "manuall installation" window). After one hour or so I terminated the process. PlayOnMac shows the virtual drive under "configuration".
No program files have been installed on the virtual drive.