I always install the proprietary one. If it is based off of Ubuntu, then you want to make sure that you install the following:
sudo apt-get build-dep wine
sudo apt-get install build-essential
sudo apt-get install multiarch-support ia32-libs
If you cannot find 'ia32-libs', don't worry about it. Then you want to:
sudo apt-get update && sudo apt-get upgrade && sudo apt-get dist-upgrade
Reboot the system, and install the proprietary drivers from AMD's website. Go there, look up your graphics card, and download the 64-bit drivers. Download it, extract it to your Downloads folder, go to a terminal, and then:
chmod +x nameofamdinstallfilethatyoudownloaded
sudo ./nameofamdinstallfilethatyoudownloaded
During the install, it will ask you if you want to install the 32-bit libraries. Choose 'yes'. When finished, let it create a xorg.conf file (it should do this automatically. If you not, when you reboot, open the AMD control center, and set your resolution, and save, and reboot. Make sure to run the control center with admin rights.), and reboot. If you have any more issues with getting all of that installed, go to your distro's or any *buntu forum ( a google search will give a LOT of results), and get it working. Then, make sure that PlayOnLinux is updated, and try to fresh-install a game, and see if it works.
If all of that does not work, then post up here with your full terminal output or debug logs from PlayOnLinux, so that we can troubleshoot further. Hope this helped. Good luck. :)
Edited by RoninDusette