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I’ve already installed Skyrim on my Ubuntu with PlayOnLinux, but now I need to install Skyrim Script Extender, and I can’t figure out how. (If you’re confused on what SKSE is, well it is basically an alternate launcher for Skyrim, useful for mods, that is found in the same folder as the normal Skyrim launcher. Any q’s about it to clarify are certainly welcome). I can’t launch SKSE like you would on Windows by using the SKSE_Launcher.exe to launch Skyrim because Linux of course naturally can’t open .exe files. Although I’ve got SKSE installed per say, it DOES NOT work (because it is exe). Can I use PlayOnLinux and Wine to launch Skyrim with SKSE like it does with the normal Skyrim launcher? How? Do I set up Skyrim Script Extender as an application similar to how I set up Skyrim? Help. 

Edited by Strevtell

I think this is what you need :

http://wiki.playonlinux.com/index.php/The_Configuration_Window  at "Run_a_.exe_in_this_virtual_drive"