Seeing as playonlinux allows you to change these paths for each virtual drive, I fail to see any reason as to why you couldn't (and shouldn't) be allowed to just set a default for future drives also. These values must be stored by Wine somewhere, and it should be possible to script it into the virtual disk setup. After all, you don't break anything more by allowing it to be set as a default, than you do by allowing it to be changed.
Is there any reasoning behind that that isn't noted in the feature request, or is it simply because it is low on the priority list that nothing has been done about it.
Edited by Gert