There is no installer for FIFA 10, yet.
However: FIFA's AppDB page tells us it runs quite well with wine 1.0.1, so you might be able to install it anyway. =)
Open up POL. Press "Tools"->"Manage wine version".
Install wine 1.0.1and close the version manager.
Press "Install" in the main POL window. In the popup window there is a small text (in the down-left corner) saying "Install an unsupported application..", press that text. Choose "Manual installation" and "Install in a new prefix". Enter a name for the prefix, something without spaces (I think FIFA10 will be a good name).
Now check "Assign wine version to a programm" (Yes, it is spelled wrong in POL)
Pick 1.0.1 in the dropdown menu. Wait.
Select the installer and just follow the instructions. (You would want a shortcut since you installed a new game)
If you have problems:
* Install DirectX End-time-user-running-files-whatever-something in the FIFA prefix. (It is in the repository) ((This is if FIFA doesn't install DirectX for you))
* Use a crack, since they suggest that on the AppDB page. Please do not ask where you can get a crack, since your question will not be answered on this site. ((But I guess using Google would help you.))
If you (somehow) get it to work:
Please tell us how you did it, or write a script for it!
(Script tutorials: http://www.playonlinux.com/en/page-2-Documentation.html
Good luck with your game!
Edited by Dr Phil